Right from the opening whistle, the Spanish side was on tip and Carlos Vela struck the side-netting with the first clear chance of the match before before thudding another effort against the post after 12 minutes, following good vision in the build-up from Seferovic.
Trading the role of finisher for supplier, Vela helped set up Real’s spectacular opening goal in the 17th minute, his cross from the left acrobatically volleyed low into the corner by Griezmann, the only attacking player occupying the Lyon box.
A goal down at half-time Lyon came out with a more positive attitude in the second half, but no sooner had Maxime Gonalons glanced a header wide, than Jagoba Arrasate’s side struck again. Seferovic was the man responsible, collecting an awkwardly bouncing ball on the left-hand side and executing a stunning half-volley from 25 metres that dipped under the crossbar and left a heavy dent in the hosts’ resolve.
Gonalons hit the bar with a header from point-blank range and Bravo scampered off his line to smother a forward run from Miguel Lopes but when Biševac brought down Vela for his second yellow card, Lyon’s night got even worse.
The Ligue 1 side are left with an uphill battle for the second leg next Wednesday, one that would have increased in scale had substitute Rubén Pardo hit the target with his late effort.